In a healthy bladder there is a natural barrier that protects the bladder lining from irritating and toxic substances found in urine. This barrier is called the glycosaminoglycan (GAG) layer. If this barrier is damaged, urine comes into direct contact with the tissues of the bladder lining and, over time, can cause damage to these tissues, as well as allowing bacteria to adhere. This damage can lead to a range of problems that cause symptoms, such as pain, urgency (the need to go to the toilet immediately), frequency (the need to go to the toilet more often) and recurrent urinary tract infections (rUTIs).
iAluRil® contains two of the most common natural components that form the protective GAG layer; hyaluronic acid (HA) and chondroitin sulphate (CS). By administering iAluRil® directly into the bladder, these components can help to repair the damage to the GAG layer and restore the bladder’s protective coating, relieving these symptoms in some patients.